R.A.M.A.D.A.

Jade Mitchell Ph.D.  |  Principal Investigator

About Us

The R.A.M.A.D.A. Group performs human health risk analysis to address risks associated with chemical and microbial stressors in multimedia environments.​ ​Our goal is to increase the utility of risk analysis for decision making and effective management of legacy and emerging contaminants.

 

Therefore, ​we develop approaches, frameworks, models and data sets to support risk characterization of poorly described hazards and exposures. Our research portfolio consists of a diverse set of projects which evaluate unintentional consequences of contaminants through exposure pathways including indoor air, water, soil, food  and commonly touched surfaces.

 

We are keenly interested in trade-offs between chemicals and microorganisms in complex urban and environmental systems like drinking water infrastructure and antibiotics within the agricultural systems.

Jade Mitchel, PhD

Principle Investigator

 expertise

We have expertise in the following general approaches

1. Systems Modeling

 

  • Conceptual
  • Statistical
  • Environmental and process
  • Life-Cycle Assessment

2. Risk Analysis

 

  • Chemical
  • Quantitative Microbial Risk Analysis (QMRA)

3.  Decision Analysis

 

  • Value of Information
  • Multi-Criteria Decision Analysis

4.  Decision Making Under Certainty

 

  • Sensitivity Analysis
  • Uncertainty Analysis

Funded Projects

2017 - 2020

Purdue University (PI): U.S. EPA (Prime Sponsor) National Priorities Research Grant “Right Sizing Tomorrow's Water Systems for Efficiency, Sustainability, and Public Health”. $912,088 (Total Project: $1,989,000)

2015 - 2017

Michigan State University (MSU), Center for Health Impacts of Agriculture (Co-PI): “Antibiotic Resistance Genes in the Environment: Organizing and Expanding MSU Capabilities for Risk Reduction”

$250,000

2016 - 2017

Michigan State University (MSU) Environmental Science and Public Policy (ESPP)  Flint Funds Proposal (co-PI): Infrastructure, Trust, and the Shadow of Flint

$26,000

2014 - 2019

NIH (PI): “Quantitative Microbial Risk Assessment Interdisciplinary Instructional Institute (QMRA III)”

$791,506

2016 - 2017

Proctor & Gamble (PI): QMRA to Assess the Effect of Antimicrobial Residual Efficacy on Risk of Infection

$51,599

2014-2017

Midland Research Institute on Value Chain Creation and the Bill and Melinda Gates Foundation (Member and Key Contributor): Global Water Pathogen Project in collaboration with UNESCO; http://www.waterpathogens.org/

$325,000

2015 - 2016

Proctor & Gamble (PI): “Quantitative Microbial Risk Assessment (QMRA) for Various P&G Antimicrobial Products on Porous and Nonporous Surfaces”

$29,952

2013

NSF PASI (Co-PI): “Quantitative Microbial Risk Assessment Innovation Institute (QMRA II)”

$99,986

2015 - 2017

Michigan State University (MSU), Center for Water Science (PI): “Citizen Science Study of Contaminant Exposures Related to Water Affordability in Detroit”

$60,000

2012 -2013

U.S. EPA and DHS (Co-PI): “Center for Advancing Microbial Risk Assessment”

$185,338

Publications

PEER-REVIEWED JOURNAL ARTICles

L. Rivers; T. Dempsey, J. Mitchell and C. Gibbs. “Environmental Regulation and Enforcement: Structures, Processes and the Use of Data for Fraud Detection,” Journal of Environmental Assessment Policy and Management Vol. 17, No. 3 (2015) doi: 10.1142/S1464333215500337

 

Y. Brooks, A. Aslan, S. Tamrakar, B. Murali; J. Mitchell; and J. Rose. “Analysis of the persistence of enteric markers in sewage polluted water on a solid matrix and in liquid suspension,” Water Research 76 (2015) 201-202

 

M. Goldsmith; C. M. Grulke; R. D. Brooks; T. R. Transue; Y. Tan; A. M. Frame; P. P. Egeghy; R. D. Edwards; D. T. Chang; R. Tornero-Velez; K. K. Isaacs; A. Wang; J. Johnson; K. Holm; M. Reich; J. Mitchell; D. Vallero; L. Phillips; M. Phillips; J. F. Wambaugh; R. S. Judson; T. Buckley; C. C. Dary. “Development of a Consumer Product Ingredient Database for Chemical Exposure Screening and Prioritization,” Food and Chemical Toxicology. (2014) 65: 269-79. doi: 10.1016/j.fct.2013.12.029

 

J. Mitchell, N. Pabon, Z. Collier, P. Egeghy, I. Linkov, D. Vallero. “A Decision Analytic Approach to Exposure-Based Chemical Prioritization,” PLoS ONE (2013) 8(8): e70911

 

J. Mitchell, J. Arnot, O. Jolliet, P. Georgopolous, S. Isukapalli, S. Dasgupta, M. Pandian, J. Wambaugh, P. Egeghy, E. Cohen-Hubal, and D. Vallero. “Comparison of Modeling Approaches to Prioritize Chemicals Based on Estimates of Exposure and Exposure Potential,”  Science of the Total Environment (2013) 458:555-567

 

J. Wambaugh, R. Woodrow Setzer, D. Reif, S. Gangwal, J. Mitchell-Blackwood, J. Arnot, O. Joliet, A. Frame, J. Rabinowitz, T. Knudsen, R. Judson, P. Egeghy, D. Vallero, and E. A. Cohen Hubal. “High Throughput Models for Exposure-Based Chemical Prioritization in the ExpoCast Project,” Environmental Science and Technology (2013) 47(15):8479-88

 

J. Mitchell-Blackwood, P. L. Gurian, R. Lee and B. Thran. “Variance in Bacillus anthracis Virulence Assessed through Bayesian Hierarchical Dose-Response Modeling,” Journal of Applied Microbiology (2012) 113 (2) 265–275

 

J. Mitchell-Blackwood, P. L. Gurian, and C. O’Donnell. “Finding Risk-Based Switchover Points for Response Decisions for Environmental Exposure to Bacillus anthracis,” Human and Ecological Risk Assessment (2011) 17(2) 489-509

 

J. Mitchell-Blackwood, P. L. Gurian, A. Kumar and M. Sarich. “Iron Oxide Coating of Geosynthetic Fibers for Water Treatment Applications,” Geosynthetic International (2008) 15(6) 471-479

 

A. Kumar, P. L. Gurian, R. H. Bucciarelli-Tieger, and J. M. Blackwood. "Iron-Oxide-Coated Fibrous Sorbents for Arsenic Removal," Journal of the American Water Works Association (2008) 100(4) 151-164

 

Y. Shin, J. M. Blackwood, I. Bae, B. W. Arey, and G. J. Exarhos. “Synthesis and Stabilization of Selenium Nanoparticles on Cellulose Nanocrystal,” Material Letters (2007) 61(21) 4297-4300

BOOK CHAPTERS

D. T. Chang, M. Goldsmith, C. M. Grulke, P. P. Egeghy, Y. Tan, J. Mitchell-Blackwood. (2014) "Data mining and informatics-based approaches for new and emerging environmental contaminants" In: Yearbook of Science and Technology, McGraw-Hill Professional, New York, NY. ISBN: 978-07-183106-2

PEER-REVIEWED CONFERENCE PAPERS/ PUBLICATIONS AS PROCEEDINGS

Mitchell, J., Weir, M., van Osch, W., and Rose, J. 2014 “The QMRA Wiki: A Social Media Tool for Interdisciplinary and Interagency Collaboration for Quantitative Microbial Risk Assessment”. In: Ames, D.P., Quinn, N.W.T., Rizzoli, A.E. (Eds.), Proceedings of the 7th International Congress on Environmental Modelling and Software, June 15-19, San Diego, California, USA. ISBN: 978-88-9035-744-2

 

Murali, B., and Mitchell, J. 2014. “The Effect of Recovery on Modeling Inactivation of Bacillus Spores on HVAC Filters”. In: Ames, D.P., Quinn, N.W.T., Rizzoli, A.E. (Eds.), Proceedings of the 7th International Congress on Environmental Modelling and Software, June 15-19, San Diego, California, USA. ISBN: 978-88-9035-744-2

 

J. Mitchell-Blackwood, M. Figueroa, C. Kokar, E. Fromm and A. Fontecchio. 2010. “Tracking Middle School Perceptions of Engineering During an Inquiry Based Engineering Science and Design Curriculum,” Proceeding of the 2010 ASEE Annual Conference and Exposition, Louisville, Kentucky

 

J. M. Blackwood, P. L. Gurian, A. Kumar, and M. Sarich. 2007. “Iron-Oxide Coated Polypropylene Fibers in Column Treatment,” Proceedings of the AWWA Annual Conference and Exposition, Toronto, Ontario, Canada

FEDERAL REPORTS

Goldsmith, Rocky, Tan, C., Chang, D. Grulke, D., Tornero-Velez, R., Vallero, D., Dary, Johnson, C.J., Egeghy, D, Mitchell-Blackwood, J., Holm, K., Reich, M., Edwards, R. and Phillips, L. 2013 “Summary Report for Personal Chemical Exposure Informatics: Visualization and Exploratory Research in Simulations and Systems (PerCEIVERS),” U.S. Environmental Protection Agency, Washington, DC, EPA/600/R13/041 (NTIS PB2013-108926)

 

J. Mitchell-Blackwood. 2010 “Dose-Response Comparisons: Bayesian Statistics,” U.S. EPA Workshop Report: State-of-the-Science for the Determination and Application of Dose-Response Relationships in Microbial Risk Assessment, Centers for Disease Control and Prevention, Atlanta, GA - EPA/600/R-10/02

 

B. Thran, R. Lee, J. Mitchell-Blackwood and P. L. Gurian. 2010 “Technical Guide 316 Supplement C2: Dose–Response Assessment for Inhalation Anthrax in Guinea Pigs Using Historical Army Data and Classical and Bayesian Statistical Methods,” Limited Distribution through the U.S. Army Public Health Command, Environmental Health Risk Assessment Program (MCHB-TS-REH), Aberdeen Proving Ground, Maryland

 

J. Mitchell-Blackwood and P. L. Gurian. 2008 “Development of Dose-Response Curves for Bacillus anthracis (Inhalation Anthrax) Using a Bayesian Approach on Historic Data,” White Paper Submitted in Support of the Physiologic Assessment of Microbial Effects (PhAME) Project, Limited Distribution through the U.S. Army Public Health Command, Environmental Health Risk Assessment Program (MCHB-TS-REH), Aberdeen Proving Ground, Maryland

OTHER PEER REVIEWED WRITINGS

J. Mitchell-Blackwood, 2010 “Are You Really Better Off?” Teach Engineering Digital Library, Available at: http://teachengineering.com/view_activity.php?url=http://www.teachengineering.org/collection/drx_/activities/drx_betteroff/drx_betteroff_activity8.xml

Presentations

J. Mitchell and V. Misra, “Selection of Surrogates for Biological Agents with Long-Term Environmental Persistence,” Society for Risk Analysis 2015 Annual Meeting, Arlington, VA (Dec. 6 – 10, 2015)

 

M. Weir and J. Mitchell, “Viz-DR: A Microbial Dose Response Visualization and Optimization Tool for

QMRA Students and Novices,” Society for Risk Analysis 2015 Annual Meeting, Arlington, VA (Dec. 6 – 10, 2015)

 

C. Gibbs, L. Rivers; T. Dempsey, and J. Mitchell, “The Use of Data in Environmental Enforcement: A Case Study”, 2015”, 71st Annual Meeting of the American Society of Criminology, Washington, DC (Nov. 18 – 21, 2015)

 

B. Murali and J. Mitchell, “Modeling the Persistence of Microbes with Long-Term Survivability in the Environment,” ASABE Annual International Meeting, Montreal, Quebec, Canada (July 2014)

 

J. Mitchell. “Pharmaceuticals and Personal Care Products in the Environment - do we care?” 63rd Michigan Onsite Wastewater Conference (January 7-9, 2014) [Invited]

 

M. Gammans*, J. Mitchell, C. Gibbs, and L. Rivers. “Environmental Enforcement: Toward Proactive Fraud Detection” ESPP Graduate Research Symposium, Michigan State University, East Lansing, MI (November 22, 2013) (Oral Presentation) *1st Place Student Presentation Winner

 

K.S. Enger, B. Murali, D. Birdsell, P. Gurian, D. M. Wagner, J. Mitchell. “Evaluating long term inactivation of bacillus spores on common Surfaces”. Society for Risk Analysis, 2013 Annual Meeting, Baltimore , MD, (December 8-11, 2013) (Peer Reviewed Abstract )

 

J. Mitchell-Blackwood. “In silico ADME and PBPK inspired dose prioritization: screening and visualization models” Society of Toxicology, Contemporary Concepts in Toxicology (CCT) Meeting: “Building for Better Decisions: Multi-Scale Integration of Human Health and Environmental Data.” US EPA, Research Triangle Park, North Carolina (May 8–11, 2012)

 

J. Mitchell-Blackwood. “From Decision Analytics for Exposure Prioritization to dietary residue exposures”

Professional Meeting: PerCEIVERS: Personal Chemical Exposure Informatics: visualization, user Experience, Research in Systems modeling and Simulations Workshop. U.S. EPA, Research Triangle Park, NC (June 26–27, 2012)

 

J. Mitchell-Blackwood. "The Development of High-Throughput Exposure Techniques for Prioritizing Chemical Risks" Society for Risk Analysis 2011 Annual Meeting, Charleston, SC (December 2011)

 

J. Mitchell-Blackwood, P. Egeghy and D. Vallero. “Challenging Exposure Prioritization Approaches” Society for Risk Analysis 2011 Annual Meeting, Charleston, SC (December 2011)

 

H. Özkaynak, P. Egeghy and J. Mitchell-Blackwood. “From SHEDS to SHEDS-lite: development of an efficient human exposure model” Society for Risk Analysis 2011 Annual Meeting, Charleston, SC (December 2011)

 

D. Wang, Z. Collier, J. Mitchell-Blackwood, J. Keisler, I. Linkov.  “Using Multicriteria Decision Analysis (MCDA) to Prioritize the Exposure Potential of Existing and Emerging Chemicals”  Society for Risk Analysis 2011 Annual Meeting, Charleston, SC (December 2011)

 

J. Mitchell-Blackwood, S. Isukapalli, P. Georgopoulos and D. Vallero.“Application of Sensitivity and Uncertainty Analysis in Chemical Prioritization,” International Society of Exposure Science (ISES) 2011 Annual Meeting, Baltimore, MD (October 2011)

 

H. Ozkaynak, J. Mitchell-Blackwood and D. Vallero. “Rapid Exposure Screening and Prioritization Using SHEDS and EFAST2”, ISES 2011 Annual Meeting, Baltimore, MD (October 2011)

J. Mitchell-Blackwood and D. Vallero. “Lessons Learned from the Exposure Based Prioritization Challenge,” Exposure-Based Chemical Prioritization Workshop II: Extending Capabilities for High-Throughput Assessment, U.S. EPA, Research Triangle Park, NC (September 2011)

 

J. Mitchell-Blackwood, P. Egeghy, and D. Vallero. “Bridging the Capabilities of Existing Human Exposure Models with Current Needs,” 2011 Association of Environmental Engineers and Science Professors (AEESP) Education and Research Conference, Tampa, FL (July 2011)

 

J. Mitchell-Blackwood, P. Egeghy, and D. Vallero. “Approaches for Rapid Exposure-Based Prioritization of Environmental Chemicals,” Society for Risk Analysis Exposure Assessment Specialty Group Tele-Seminar (via internet) (June 2011) [Invited]

 

J. Mitchell-Blackwood and P.L. Gurian. “Bayesian model comparison of dose-response models for biological agents,” Society for Risk Analysis 2010 Annual Meeting, Salt Lake City, UT (December 2010)

 

V. Corella-Barud, S. Flores, H. Galada, J. Graham, P. Gurian, J. Mitchell-Blackwood, T. Montoya, C.O'Donnell , F. Perez, G. Velazquez. "Risk Management: Thinking and Doing," invited presentation to Environmental Science and Engineering Doctoral Program, University of Texas at El Paso (via internet) (April 2010) [Invited]

 

P. Gurian, T. Hong, J. Mitchell-Blackwood, I. Solon, C. Haas, N. D. Ward, Y. Huang, C. O’Donnell, and H. Perez. “Responding to Bioterrorism: From Risk Assessment to Risk Management,” The Fourth Annual DHS University Network Summit, Washington, DC (March 2010) [Invited]

 

J. Mitchell-Blackwood and P. L. Gurian. “Dose Response Method Comparisons: Bayesian Statistics”, EPA/CDC Workshop on State-of-the-Science for the Determination and Application of Dose-Response Relationships in Microbial Risk Assessment, Atlanta, GA (April 2009) [Invited]

 

J. Mitchell-Blackwood, P. L. Gurian, and C. O’Donnell. “An Evaluation of the Risk Threshold for Prophylaxis and Treatment After an Anthrax Release,” Drexel Engineering Research Symposium, Drexel University, Philadelphia, PA (March 2009) [Invited]

 

J. Mitchell-Blackwood, P. L. Gurian, and C. O’Donnell. “An Evaluation of the Risk Threshold for Prophylaxis and Treatment After an Anthrax Release,” The Third Annual DHS University Network Summit and Student Day, Washington, D.C., (March 2009) [Invited]

 

J. Mitchell-Blackwood, P. L. Gurian, and C. O’Donnell. “An Evaluation of the Risk Threshold for Prophylaxis and Treatment After an Anthrax Release,” Society for Risk Analysis 2008 Annual Meeting, Boston, MA (December 2008)

 

J. Mitchell-Blackwood, T. Hong, N. D. Ward and P. L. Gurian. “Relating Human Health Risk to Environmental Concentrations of B. anthracis Using Analytic Models,” 11th Annual Force Health Protection Conference of the U. S. Army Center for Health Promotion and Preventative Medicine (USACHPPM), Albuquerque, NM (August 2008)

 

J. Mitchell-Blackwood, P. L. Gurian, and M. H. Weir. "A Hierarchical Model for Probabilistic Dose-Response Assessment of Bacillus anthracis," The Second Annual DHS University Network Summit and Student Day, Washington, D.C. (March 2008)

 

J. Mitchell-Blackwood, P. L. Gurian, and M. H. Weir. “A Bayesian statistical modeling approach for Bacillus anthracis,” Society for Risk Analysis 2007Annual Meeting, San Antonio, TX (December 2007)

 

J. Mitchell-Blackwood and P. L. Gurian. “Performance of Polypropylene Geosynthetic Filters Under Pressurized Hydraulic Flow Conditions: Headloss and Iron Oxide Coating Retention,” Drexel Engineering Research Symposium, Drexel University, Philadelphia, PA (April 2007).

 

A. Kumar, P. L. Gurian, R. H. Bucciarelli-Tieger, and J. Mitchell-Blackwood. “Iron-Oxide-Coated Fibrous Sorbents for Arsenic Removal,” Drexel Engineering Research Symposium, Drexel University, Philadelphia, PA (April 2007

TEAM

Principle Investigator

Dr. Jade Mitchell

Director of the Ramada Research Group

jmitchellphd.com

Post-Doctoral Research Associates

Dr. Umesh Adhikari

(2015 - present) - QMRA III Course Manager, microbial risk assessment case studies

Dr. Sina Akram

(2016 - present) - Evaluating the fate and transport of antimicrobial pathogens and genes in the environment

Past Post-Doctoral Research Associates

Dr. Yiseul Kim

(2016 - present) - Modeling persistence of DNA markers in water matrices

Dr. Kyle Enger (2013)

 CAMRA persistence modeling code development and analysis of Bacillus surrogates

Dr. Amanda Herzog (2014 - 2015)

 QMRA III Course Manager

Ph.D Graduate Research Assistants

Alexandre Chabrelie (2015 - present) - Modeling risk associated with antimicrobial resistance from farm to fork

M.S. Graduate Research Assistants

Kara Dean (Graduated .....) - .......

 

Pouyan Hatami (Graduated December 2016) - Applicability of data driven methods to assess data mishandling in wastewater treatment plant self-reported discharge data

 

Bharathi Murali (Graduated December 2014) - Comparison of the persistence and recovery Bacillus species surrogates

Undergraduate Research Assistants

Emily Willis. Biosystems Engineering MSU Summer 2016-present

Yara Fakhoury. Biosystems Engineering MSU Spring 2016 - present

Shane Peterson. Biosystems Engineering MSU Spring 2016

Viswarup Misra. Biological Sciences & Bioengineering IIT Kanpur Summer 2015

Austin Wissler. Biosystems Engineering MSU Fall 2014 – Spring 2016

Damanpreet Singh. Computer Science MSU Fall 2014 - present

Eric Blackowicz. Biomedical Laboratory Science; MSU Summer 2013

Matthew Gammans. Biosystems Engineering; MSU Spring 2013 -Spring 2014

Andrew Bruce. Environmental Microbiology; MSU Fall 2012 - Spring 2013

Alexa Jones. Biosystems Engineering; MSU Fall 2012 - Spring 2013

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